To reach Saturday's semi final they disposed of Fermanagh two weeks ago while Tyrone who have the favourites tag seen off Derry and Armagh.
It's a tie that has followers of northern football craving the derby at Breffni Park.
Donegal Manager Declan Bonner has been looking ahead to the game with Oisin Kelly and he says their preparation for the Tyrone battle has been good...
Donegal v Tyrone in the Ulster Semi Final on Saturday 8th June will be LIVE on Highland Radio Sport in association with Gal Oil – Fuel You Can Trust at Clady Bridge Castlefin. Your One Stop Shop for all your fuel needs, with top rates given on sterling.