It's understood two people have died and several others are seriously injured in a road traffic crash outside Newtowncunningham.
Emergency services are currently at the scene.
The crash occured on the Letterkenny side of the village at approximately 2.30 this afternoon.
It's believed a number of cars were involved in the incident.
The road is currently closed and local diversions are in place.
There are no further details at this stage.