Derry City, who have been struggled to find the net and who were held scoreless by Bray and the Brandywell on Friday night, make the trip south to take on bottom of the table Limerick.
The leaders Dundalk will be looking to get back to winning ways as they host Galway United.
Hot on their heels are Cork City, who also have home comforts tonight - they welcome Longford to Turner's Cross.
Shamrock Rovers travel to the Carlisle Grounds to face Bray Wanderers.
Bohemians make the journey to Sligo and St. Pat's will look for another win as they entertain Drogheda.
Kick-off in all those games is at 7.45.