Paul Durcan and Eamon Mc Gee make their first appearances of the year while Mark Mc Hugh and Gary Mc Fadden will also start against the Erne County.
For goalkeeper Durcan and McGee it will be their first time to line out since the All Ireland defeat in September.
McHugh is named after missing last weekend’s win over Queens with a quad muscle problem and Glenswilly’s McFadden gets a second start in three games.
Newcomers Eoin Mc Hugh and Ciaran Mc Ginley retain their places while Daniel Mc Laughlin, Hugh Mc Fadden and Marty O'Reilly will make up full forward line once again.
Oisin Kelly and Declan Bonner will have a LIVE GAA Special from Ballybofey on Wednesday Night in association with Evolve Menswear, starting at 7.55pm.
Donegal Team to play Fermanagh 14/01/2015 in the McKenna Cup
1. Paul Durcan.
2. Eamonn Doherty, 3. Eamonn McGee, 4. Declan Walsh
5. Eoin McHugh, 6. Frank McGlynn, 7. Ciarán McGinley
8. Christy Toye, 9. Martin McElhinney,
10. Mark McHugh, 11. Odhrán Mac Niallais, 12. Gary McFadden
13. Daniel McLaughlin, 14. Hugh McFadden, 15. Marty O’Reilly