Gardai said perfumes and other cosmetics were stolen in a burglary at her Cara pharmacy in Bundoran, Co. Donegal.
Ramona, 37, a star of Dragon’s Den on RTE, runs a chain of Cara pharmacies along with her husband Canice in a €25 million business in the north-west.
Her Bundoran store was closed throughout Monday while detectives investigated the break-in through a rear entrance.
A senior Garda officer said:it was a well-planned burglary.
It is believed the stolen perfumes could be sold at cut-rate prices on Christmas markets.
CCTV footage was being examined and gardai conducted house-to-house inquiries in their search for clues.