The crash happened on the N13 at Lisfannon in Burt at around 10.30pm.
The motorcyclist was fatally injured when he was involved in a collision with two cars. He was pronounced dead at the scene and his body was removed to Letterkenny General Hospital.
One of the drivers, a man in his 30's, was taken to hospital in Derry with minor injuries while, the driver of the second car was uninjured.
Superintenant Eugene McGovern is appealing for information: