Centre-forward Shay McGuigan will make his senior championship debut for Tyrone after being named on a new-look half-forward line along with Emmett McKenna.
Connor McAliskey has also been promoted to the starting line-up while PJ Quinn comes into the defence at corner back.
Martin Penrose, Ronan O’Neill , Conan Grugan, and Justin Mc Mahon drop to the bench.
Tyrone minor captain Conor McKenna has been named on the bench after he was called-up to the senior squad earlier this week.
1 - Niall Morgan - Éadan na dTorc, 2 - Aidan McCrory - Aireagal Chiaráin, 3 - Ronan McNamee - Achadh Uí Aráin, 4 - PJ Quinn - Baile na Móna, 5 - Ronan McNabb - An Droim Mhór, 6 - Mattie Donnelly - Trí Leac, 7 - Peter Harte - Aireagal Chiaráin, 8 - Colm Cavanagh - An Mhaigh, 9 - Sean Cavanagh (C) - An Mhaigh, 10 - Emmett McKenna - Eaglais, 11 - Shay McGuigan - Ard Bó, 12 - Ciaran McGinley - Aireagal Chiaráin, 13 - Darren McCurry - Éadán na dTorc, 14 - Stephen O’Neill - Clann na nGael, 15 - Connor McAliskey - Cluain Eo.