Invest Northern Ireland is to spend £7m buying and developing 22 acres of industrial land in Strabane.
Arlene Foster, who has retained the enterprise ministry, said the Strabane had been chosen as a priority areas where industrial land was needed to support investment.
The Invest NI strategy is aimed at encouraging economic development.
Units on the development should be available for sale from summer 2013.
West Tyrone MP, Pat Doherty welcomed the news, and he said he was hopeful that jobs would now be created in the town: